Multidisciplinary NET board
Nuclear medicine, oncology, surgery, pathology, radiation oncology and radiology decide the optimal strategy together.
Neuroendocrine Tumor (NET) Center in Turkey
Diagnosis and targeted therapy for neuroendocrine tumors
Precise molecular imaging, a specialized NET tumor board and targeted therapies (PRRT) — one of the few centers in the region to bring diagnosis and treatment together under one roof.
- Free medical second opinion within 48 hours
- Ga-68 DOTATATE PET/CT and Lutetium-177 PRRT in the same center
- Medical interpreter, transfers and accommodation — fully arranged
- Ga-68 DOTATATE PET/CT
- PRRT · Lutetium-177
- Dedicated NET board
- Ki-67 pathology
International accreditations and recognition
JCI 
OECI 
ESMO 
Planetree Gold 
World's Best Hospitals 
HealthTürkiye
Early and precise diagnosis
Specialized imaging and pathology expertise for NET
Diagnosing neuroendocrine tumors requires dedicated methods — from functional imaging to the pathological grading that directly guides treatment:
Ga-68 DOTATATE PET/CT — the functional imaging standard for somatostatin receptor-positive NETs, with exceptional accuracy.
FDG PET/CT — for high-grade or dedifferentiated neuroendocrine carcinomas.
Biomarkers — Chromogranin A, NSE and hormone panels to detect and monitor tumor activity.
Endoscopic ultrasound (EUS) and biopsy — minimally invasive sampling for pancreatic and gastrointestinal NETs.
Advanced pathological grading (Ki-67) — G1/G2/G3 classification, which directly guides the treatment decision.
Multidisciplinary NET board — every case is reviewed before the plan is set.
Nuclear medicine · Theranostics
See the tumor and treat it with the same type of molecule
Molecular imaging – Targeted therapy – Minimal side effects
Many neuroendocrine tumors express somatostatin receptors that can be both visualized and targeted with radiolabeled compounds. Our nuclear medicine department uses internationally standardized protocols and next-generation digital PET/CT with AI-integrated imaging.
Lutetium-177 DOTATATE PRRT delivers radiation directly into receptor-positive tumor cells — an effective option for advanced NETs that protects healthy tissue.
Personalized treatment options
The right treatment for the tumor's origin, grade and extent
The plan depends on the tumor's primary origin, its grade, hormone secretion and how far it has spread. At Anadolu we offer:
PRRT — Lutetium-177 DOTATATE: targeted radionuclide therapy for advanced, somatostatin receptor-positive NETs.
Surgical resection: for localized or resectable disease (gastrointestinal tract, pancreas and other sites).
Somatostatin analogues (SSA): octreotide / lanreotide for tumor and symptom control in functional NETs.
Targeted therapy and chemotherapy: everolimus, sunitinib, temozolomide for progressive or high-grade disease.
Liver-directed therapies: including transarterial embolization for liver metastases.
Hormone management: for carcinoid syndrome, insulinoma, gastrinoma and other hormonal syndromes.
Surgical treatment
Precision surgery with organ preservation
Precision surgery – Organ-preserving techniques – Experienced oncologic surgeons
For localized or resectable NETs, surgical removal remains the cornerstone of treatment. Our team specializes in the oncologic resection of NETs of the gastrointestinal tract, pancreas, appendix and other sites:
Pancreatic NETs: distal pancreatectomy (minimally invasive or open), enucleation or the Whipple procedure, depending on location and size.
Gastrointestinal NETs: small-bowel resection with mesenteric lymph node dissection for carcinoid tumors.
Appendiceal NETs: appendectomy or right hemicolectomy, depending on size and grade.
Liver debulking: reducing tumor burden for a better response to systemic or radionuclide therapies.
Minimally invasive approaches: laparoscopic and robotic techniques for faster recovery.
Radiation oncology
Precision radiotherapy as part of the NET board
Radiotherapy plays an important supporting role in NET management — for local control, palliation and the treatment of metastatic lesions:
SBRT/SABR: high, focused doses in a small number of sessions, for localized lesions or oligometastatic disease.
MR-Linac: real-time MRI-guided radiotherapy — ideal for abdominal and pelvic lesions near critical structures.
Palliative radiotherapy: relief of symptomatic bone metastases and locally advanced lesions.
What we treat
Types of neuroendocrine tumors we treat
Neuroendocrine tumors can develop in many parts of the body. Our team covers the entire spectrum:
Gastroenteropancreatic NETs (GEP-NET): small-bowel carcinoids, pancreatic NETs (insulinoma, gastrinoma, glucagonoma) and non-functional forms.
Lung NETs: typical and atypical carcinoids of the lung.
Poorly differentiated neuroendocrine carcinomas (NEC): large-cell and small-cell types.
Pheochromocytoma and paraganglioma: rare tumors of the adrenal gland and the sympathetic nervous system.
Merkel cell carcinoma: a rare but aggressive cutaneous neuroendocrine tumor.
Functional NETs with hormonal syndromes: carcinoid syndrome, Zollinger-Ellison syndrome, VIPoma.
Why Anadolu
Why Anadolu Medical Center for NET?
A complete theranostics center, built around a board dedicated to neuroendocrine tumors.
Theranostics expertise
One of the few centers in the region with DOTATATE PET/CT and Lutetium-177 PRRT under one roof.
Advanced NET pathology
Ki-67 grading, immunohistochemistry and molecular profiling — a diagnosis you can rely on.
Johns Hopkins Medicine affiliation
Continuous access to the latest protocols, expertise and standards in cancer care.
Prof. Dr. Kezban Berberoğlu
Nuclear Medicine · Theranostics
Medical second opinion
Verify your diagnosis with the Theranostics & NET team
Send your medical documents (imaging, biopsy with Ki-67, hormone tests) and our dedicated neuroendocrine tumor board will evaluate your case free of charge: diagnosis, treatment options — including your eligibility for PRRT — and an estimated cost plan.
- 100% free and confidential
- Response within 48 hours
- No obligation whatsoever
NET team
The experts of the neuroendocrine tumor board
Nuclear medicine, pathology, medical oncology, surgery, gastroenterology and radiation oncology — complete expertise for NET.
Prof. Dr. Kezban Berberoğlu
Nuclear Medicine · Theranostics
Prof. Dr. Hüseyin Baloğlu
Pathology
Assoc. Prof. Dr. Eda Tanrıkulu Şimşek
Medical Oncology
Prof. Dr. Bülent Karagöz
Medical Oncology
Prof. Dr. Necdet Üskent
Medical Oncology
Prof. Dr. Şeref Kömürcü
Medical Oncology
Dr. Sinan Karaaslan
Medical Oncology
Prof. Dr. Banu Atalar
Radiation Oncology
Prof. Dr. Sedat Karademir
General Surgery · HPB
Prof. Dr. Altan Kır
Thoracic Surgery
Prof. Dr. Ahmet Melih Özel
Gastroenterology
Assoc. Prof. Dr. Hasan Murat Gürsoy
Gastroenterology
Assoc. Prof. Dr. Ayhan Erdemir
General Surgery
Every case is discussed by the multidisciplinary board dedicated to neuroendocrine tumors.
Testimonials
What our patients say
International patients from around the world, treated at Anadolu.
Patient story Life-changing care at Anadolu
Patient from Nigeria Freeman's journey — strength and resilience
Patient from Cuba Jose Manuel Inclán Embade — from Cuba to Türkiye
Services for international patients
We support you at every step of your journey
We understand that travelling abroad for cancer treatment can be challenging. Our international patient team takes care of everything.
100% FREE — all the services below
Medical interpreter
A dedicated interpreter accompanies you at consultations, investigations and admission — free of charge.
Dedicated coordinators
Patients from 65+ countries, assistance in 18 languages — including English.
Travel arrangements
Full assistance with travel, visa (where required) and accommodation.
Airport transfers
Free transfers to and from the airport, with a dedicated driver.
Second opinion within 48h
Free evaluation of your documents by the oncology team.
Full coordination
Seamless liaison between doctors, hospital and insurer, with your discharge documents provided in English.
Send your medical documents today — a specialist will contact you the same day.
Frequently asked questions
Questions about neuroendocrine tumors
Can’t find your answer? Talk directly to a patient coordinator — no obligation.
It is the most sensitive imaging technique for somatostatin receptor-positive NETs: it detects the primary tumor, affected lymph nodes and metastases in a single scan, and it establishes whether you are eligible for PRRT. It is superior to conventional CT or MRI for staging NETs.
PRRT (peptide receptor radionuclide therapy) delivers radiation directly into tumor cells that express somatostatin receptors. It is intended for advanced or metastatic receptor-positive NETs — eligibility is confirmed with a Ga-68 DOTATATE PET/CT and an evaluation by the NET board.
Many NETs grow slowly, but their behavior varies enormously depending on grade (Ki-67) and location. Correct classification and the decision of a dedicated NET board make the difference between simple monitoring, organ-preserving surgery or targeted therapies — that is why specialized expertise matters.
They are a very useful starting point. Our pathology team can re-evaluate your existing slides, perform Ki-67 grading, immunohistochemistry and additional molecular profiling, and DOTATATE imaging completes the staging if needed.
Nothing. You send your medical documents and the Theranostics & NET board responds free of charge within 48 hours with your treatment options and a transparent cost estimate. No obligation whatsoever.
Yes. Our international patient team speaks English, a medical interpreter accompanies you to consultations and investigations, and your English-speaking patient coordinator stays in constant contact with you and your family, including after you return home.
About us
About Anadolu Medical Center in Istanbul, Turkey
Anadolu Medical Center is a state-of-the-art multispecialty hospital in Istanbul, established by the Anadolu Foundation in 2005, with non-profit status and a unique affiliation with Johns Hopkins Medicine USA.
The affiliation with Johns Hopkins Medicine provides continuous access to the latest innovations, expertise and technological advances — on a par with the world's best hospitals.
Contact
Send us your message
Fill in the form and a patient coordinator will contact you the same day. A specialist medical opinion — within 48 hours.
Anadolu Medical Center — Istanbul
Cumhuriyet Mah., 2255 Sok. No: 341400 Gebze / Kocaeli, Turkey
Response within 48 hours
Request a free review of your case
Our oncology team reviews your documents and comes back with a concrete plan.